Aortic wall stiffness and microcalcification in inherited thoracic aortopathies
نویسندگان
چکیده
منابع مشابه
Alteration in Aortic Wall Stiffness and Accumulation
ardiovascular disease has been recognized as the most common complication of type II diabetes mellitus (DM). Although hyperinsulinemia, insulin resistance and the abnormal lipoprotein profile have important roles in macrovascular disease development,1–4 considerable controversy exists regarding the process of arterial wall damage. Nevertheless, most studies have examined aortic damage in an ani...
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Background Thoracic aortic aneurysm (TAA) disease is an often asymptomatic, insidious process that includes structural aortic changes, dilation, and eventually causes death. Aneurysm prevalence exceeds 4% and is the 15th leading cause of death in the US. TAA disease is associated with congenital and acquired defects in the aortic wall including elastin derangements, increased collagen, glycosam...
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Systolic hypertension is associated with increased pulse pressure (PP) and increased risk for adverse cardiovascular outcomes. However the pathogenesis of increased PP remains controversial. One hypothesis suggests that aortic dilatation, wall stiffening and increased pulse wave velocity result from elastin fragmentation, leading to a premature reflected pressure wave that contributes to elevat...
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The aorta is the largest artery that delivers blood from the heart to the rest of the body, and many cardiovascular diseases often occur on the aortic arch. The complex mechanical interaction between pulsatile blood flow and wall dynamics in the aortic arch model was simulated by means of computational loose coupling fluid-structure interaction analyses. This study investigates the pulsatile fl...
متن کاملThoracic aortic wall shear stress atlases in patients with bicuspid aortic valves
Background Wall shear stress (WSS) may be associated with the onset and development of aortopathy in the presence of bicuspid aortic valve (BAV) [Michelena, JAMA (2011)]. The use of ‘aortic atlases’ of 3D WSS vectors allows for systematic analysis of WSS differences between large patient cohorts. In this study, a comparison is performed between WSS atlases of BAV patients, BAV patients with aor...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2020
ISSN: 0195-668X,1522-9645
DOI: 10.1093/ehjci/ehaa946.2314